Rachel Holden Queens University, Canada

Dr. Rachel M. Holden is a nephrologist and a Professor in the Department of Medicine with a cross-appointment to the Department of Biomedical and Molecular Sciences at Queen's University. She joined the faculty in 2001.
Dr. Holden and her associates study basic mechanisms of vascular calcification in chronic kidney disease. She is particularly interested in the role of phosphate as novel risk factor for cardiovascular disease in the general population.
A major focus of her research program is clinical, basic and translational aspects of vitamin K metabolism and specifically the role of vitamin K in the inhibition of vascular calcification. She is currently leading the CIHR-funded iPACK-HD clinical trial – a randomized controlled trial that will evaluate whether vitamin K supplementation attenuates the progression of calcification in patients with end stage kidney disease.
Dr. Holden's clinical interests include mineral bone disorders in chronic kidney disease and hemodialysis patients.
Dr. Holden holds investigator-initiated research funding from Sanofi and OPKO Renal.